Turmeric is a tall plant that grows in Asia and Central America and is also known as Indian saffron or golden spice.
Turmeric, which is used in cooking and sold in supermarkets, extracted from the plant’s roots. Processed turmeric’s vivid yellow colour has encouraged numerous cultures to utilize it as a dye. Turmeric powder is also a key ingredient in curry powder. Turmeric is also available commercially in a variety of forms, including capsules, teas, powders, and extracts.
Turmeric contains the active component curcumin, which has powerful biological characteristics. Turmeric is recommended for a variety of health concerns in Ayurvedic medicine, an ancient Indian therapeutic approach. Chronic pain and inflammation are examples of this. Turmeric is being studied in Western medicine as a painkiller and healing agent.
The function of Curcumin
● Hay fever. Sneezing, itching, runny nose, and shortness of breath have been observed to be reduced when curcumin, a substance present in turmeric, is consumed.
● Depression. Curcumin, a molecule contained in turmeric, has been shown to lessen depression symptoms in people taking antidepressants in a vast number of studies.
● High levels of cholesterol or other fats (lipids) in the blood (hyperlipidemia). Turmeric has been shown to reduce triglyceride levels in the blood. The effects of turmeric on cholesterol levels, on the other hand, are contradictory. In reality, there is a wide range of turmeric products available. As a result, it’s difficult to say which turmeric product is best.
● Accumulation of fat in the liver in people who drink alcohol or without alcohol (non-alcoholic fatty liver disease or NAFLD). Intake of turmeric extract has been shown in studies to improve symptoms of liver injury in people who have liver disease that isn’t caused by alcohol. It also aids in the prevention of the buildup of additional fat in the liver in people who have this problem.
● Osteoarthritis. Several studies have indicated that using turmeric extract alone or in combination with other herbal ingredients can help people with knee osteoarthritis reduce pain and improve function. Turmeric has been shown in a few studies to be as effective as ibuprofen in reducing osteoarthritis pain. In people with osteoarthritis, it appears to be less effective than diclofenac in reducing pain and improving function.
● Itching. Long-term itching in people with the renal illness can be reduced by taking turmeric three times a day for eight weeks, according to research. Furthermore, an early study suggests that taking some combination products comprising curcumin, black pepper or chilli on a daily basis for four weeks can lessen the severity of hives and enhance the quality of life in those with hives. It is a long-term condition caused by mustard gas.
● Alzheimer disease. The use of turmeric or the molecule curcumin was found to have no effect on Alzheimer’s symptoms. In fact, some studies suggest that turmeric can influence the way people with this illness think. However, trials to date have been few and of poor quality, and current evidence does not support the use of turmeric for Alzheimer’s disease.
● Stomach ulcer. A small number of studies have found that taking turmeric three times a day for eight weeks does not help with stomach ulcers. Furthermore, taking turmeric powder four times a day for six weeks was found to be less effective than using traditional antacids.
● Skin damage caused by radiation therapy (radiation dermatitis). When undergoing radiation treatment, curcumin intake was found to be ineffective in preventing skin issues.
● Deterioration of memory and thinking skills occurs normally with age. Curcumin has been shown to aid memory and attention in older adults in several studies. A handful of these adults had shown evidence of modest mental impairment prior to taking curcumin. Curcumin, on the other hand, does not improve mental performance in older adults who do not show evidence of mental decline, according to other research.
● Asthma. In adults and children, adding turmeric to normal asthma therapy did not enhance lung function or lessen most asthma symptoms. However, adding turmeric to the therapy of typical childhood asthma can lessen the use of inhalers and reduce the symptoms of waking up at night.
● A blood disorder that reduces the level of protein in the blood or haemoglobin (beta-thalassemia). People who have beta-thalassemia may require blood transfusions. Iron levels in the blood may rise as a result of this operation. Curcumin may help people with beta-thalassemia reduce the amount of iron in their blood, according to preliminary studies.
● Severe skin reactions caused by cancer drug treatment (chemotherapy-induced acute erythema). Turmeric consumption was found to have no effect on skin responses in people taking the cancer medication capecitabine. In fact, it can help to alleviate the signs and symptoms of severe skin responses.
● Non-cancerous growths in the large intestine and rectum (colorectal adenoma). Preliminary research shows that intake of turmeric extract does not diminish the quantity of development in the gut for those with familial adenomatous polyposis, according to preliminary studies.
● Colon cancer, rectal cancer. According to a preliminary study, consuming turmeric extract and Javanese turmeric extract can help to stabilize some tumours. Furthermore, early research suggests that taking curcumin daily for 30 days can lower the number of precancerous glands in the colon in people who are at high risk of getting cancer.
● Surgery to increase blood flow to the heart (CABG surgery). Curcuminoid intake, starting three days before surgery and continuing for five days after surgery, appears to reduce the risk of a heart attack after bypass surgery, according to preliminary studies.
● A type of inflammatory bowel disease (Crohn’s disease). Some data suggests that taking curcumin every day for a month can help people with Crohn’s disease have fewer bowel motions, diarrhoea, and abdominal pain.
● Diabetes. Turmeric use appears to reduce diabetes in those with prediabetes, according to preliminary studies.
● Digestion (dyspepsia). According to some studies, consuming turmeric four times a day for seven days can help reduce stomach pain.
● Muscle pain due to exercise. Turmeric appears to lessen muscle discomfort after exercise, according to a preliminary study.
● Mild gum disease (gingivitis). According to preliminary studies, saffron mouthwash reduces the symptoms of gum disease and germs in the mouth of people with gingivitis in the same way that ordinary mouthwash does.
● Gastrointestinal tract infections can cause ulcers (Helicobacter pylori or H. pylori). According to preliminary research, taking turmeric every day for four weeks is less successful than using standard therapies to get rid of specific bacteria (H. pylori) that can cause stomach ulcers. According to other research, using turmeric with traditional treatment to eliminate this bacterium (H. pylori) does not prove that traditional treatment is more effective. However, it can aid in the alleviation of stomach discomfort.
● Disorders of the large intestine that cause abdominal pain (irritable bowel syndrome or IBS – Irritable Bowel Syndrome). According to early studies, taking turmeric extract every day for eight weeks can help people with IBS feel better. Other preliminary research suggests that taking turmeric and fennel capsules for 30 days will help people with IBS reduce pain and enhance their quality of life.
● Joint pain. Research shows that consuming certain products containing turmeric and other ingredients three times a day for 8 weeks can reduce the severity of joint pain. But it was found not to help reduce joint spasms or improve joint function.
● A type of inflammatory bowel disease (ulcerative colitis). Some preliminary research suggests that taking curcumin along with standard therapy to treat ulcerative colitis can improve symptoms and increase healing time. However, this study was of poor quality, and when the data of this and another study were combined, curcumin was found to have no effect on the cure rate. As a result, further high-quality research is needed to identify curcumin’s impact on ulcerative colitis.
● Swelling (inflammation) of the eyes (uveitis). Preliminary research suggests that curcumin intake can improve long-term inflammatory symptoms in the eye.
More evidence is needed to evaluate turmeric for this use:
● Liver and gallbladder problems.
● Menstrual problems.
● Other circumstances.
Side Effects of Curcumin
In humans, an 8-gram dose of curcumin was found to have no significant side effects. However, in such assessments, a more extensive long-term investigation is still required.
The interactions of Curcumin
- Curcumin in excessive amounts can also cause nausea and stomach distress. Because piperine increases intestinal permeability, combining curcumin with piperine can result in poorer pharmacological reactions. However, the safety of various curcumin formulations has yet to be determined.
- Curcumin interacts with anticoagulant and antiplatelet medications that reduce blood clotting.
- Curcumin has been shown to slow the clotting of blood. Turmeric consumption along with drugs that reduce blood coagulation can raise the risk of bruising and bleeding.. Aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, etc), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin ), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others are some of the medications that prevent blood clotting .
Dosage of Curcumin
- For fever. 500 mg of curcumin was used daily for 2 months.
- For depression. 500 mg of curcumin was taken twice daily, singly or together with 20 mg of fluoxetine daily, for 6–8 weeks.
- For high cholesterol levels or other fats (lipids) in the blood (hyperlipidemia): 1.4 grams of curcumin extract in two divided doses on a daily basis for 3 months was – used.
- For fat accumulation in the liver in people who drank little or no alcohol (non -alcoholic fatty liver disease or NAFLD): 500 mg of product containing 70 mg of curcumin was used daily for 8 weeks. In addition, 500 mg tablets (Meriva, Indena) containing 100 mg of curcumin were used twice daily for 8 weeks.
- For osteoarthritis: Typically, 500 mg of curcumin extract is taken two to four times a day for 1-3 months.
- For itching: 1500 mg of turmeric in three divided doses daily for 8 weeks. In addition, a special product containing curcumin extract (C3 Complex, Sami Labs LTD) along with black pepper or chilli is used daily for 4 weeks.
- Orally: For levels of high cholesterol or other fats (lipids) in the blood (hyperlipidemia): 1.4 grams of turmeric extract in two divided doses on a daily basis for 3 months has been used in children at least 15 years of age.